CYP2C19 Genotype‐Guided Antiplatelet Therapy After Percutaneous Coronary Intervention in Diverse Clinical Settings

…, JC Coons, J Giri, CW McDonough… - Journal of the …, 2022 - Am Heart Assoc
Background Studies have demonstrated increased risk of major atherothrombotic events in
CYP2C19 loss‐of‐function (LOF) variant carriers versus non‐carriers treated with clopidogrel …

Impact of the CYP2C19*17 Allele on Outcomes in Patients Receiving Genotype‐Guided Antiplatelet Therapy After Percutaneous Coronary Intervention

…, Y Gong, RP Kreutz, CW McDonough… - Clinical …, 2021 - Wiley Online Library
Genotyping for CYP2C19 no function alleles to guide antiplatelet therapy after percutaneous
coronary intervention (PCI) improves clinical outcomes. Although results for the increased …

Impact of the ABCD‐GENE score on clopidogrel clinical effectiveness after PCI: a multi‐site, real‐world investigation

…, N Kulick, JG Malave, CW McDonough… - Clinical …, 2022 - Wiley Online Library
The Age, Body mass index, Chronic kidney disease, Diabetes mellitus, and CYP2C19
GENEtic variants (ABCD‐GENE) score was developed to identify patients at risk for diminished …

Effectiveness of Clopidogrel vs Alternative P2Y12 Inhibitors Based on the ABCD-GENE Score

…, RA Kerensky, N Kulick, CW McDonough… - Journal of the American …, 2024 - jacc.org
Background An ABCD-GENE (age, body mass index, chronic kidney disease, diabetes, and
CYP2C19 genetic variants) score ≥10 predicts reduced clopidogrel effectiveness, but its …

Evaluation of Potential Racial Disparities in CYP2C19‐Guided P2Y12 Inhibitor Prescribing After Percutaneous Coronary Intervention

…, JC Coons, Y Gong, CW McDonough… - Clinical …, 2023 - Wiley Online Library
Black patients suffer worse outcomes after percutaneous coronary intervention (PCI) than
White patients. Inequities in antiplatelet prescribing may contribute to this health disparity. We …

Propagation protocol for blue elderberry (Sambucus nigra L. ssp. cerulea (Raf.) Bolli)

TC McDonough, DJ Regan, AS Nelson - Native Plants Journal, 2018 - npj.uwpress.org
We present our techniques for producing blue elderberry (Sambucus nigra L. ssp. cerulea (Raf.)
Bolli [Adoxaceae]) from seeds at a container nursery in northern Idaho. By applying a …

IMPACT OF THE ABCD-GENE SCORE ON P2Y12 INHIBITOR CLINICAL EFFECTIVENESS AFTER PCI: A MULTI-SITE, REAL-WORLD INVESTIGATION

…, Y Gong, RA Kerensky, C McDonough… - Journal of the American …, 2023 - jacc.org
Background An ABCD-GENE (Age, Body mass index, Chronic kidney disease, Diabetes
and CYP2C19 Genotype) score≥ 10 is predictive of an increased risk of major …

Demonstrating high reliability on accountability measures at the Johns Hopkins Hospital

…, C Thomas, T Tolson, J Trost, C Walters, C Ware… - The Joint Commission …, 2013 - Elsevier
Article-at-a-Glance Background Patients continue to suffer preventable harm from the
omission of evidence-based therapies. To remedy this, The Joint Commission developed core …

[HTML][HTML] The Role of Preoperative Bilateral Breast Magnetic Resonance Imaging in Patient Selection for Partial Breast Irradiation in Ductal Carcinoma In Situ

…, LA Vallow, M McDonough, CS Thomas… - International Journal of …, 2012 - hindawi.com
Purpose. Women with ductal carcinoma in situ (DCIS) are often candidates for breast-conserving
therapy, and one option for radiation treatment is partial breast irradiation (PBI). This …

Grounding speech and silence: Cataphaticism and apophaticism in Denys and Aquinas

C McDonough - Irish theological quarterly, 2011 - journals.sagepub.com
This article investigates the interplay of cataphatic and apophatic theology in the works of
Denys (Pseudo-Dionysius) and Aquinas. In each case, the reasons given for the possibility of …